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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
46.97
Human Site:
S477
Identified Species:
79.49
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S477
N
I
D
Y
T
V
H
S
V
R
R
A
L
E
N
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S477
N
I
D
Y
T
V
H
S
V
R
R
A
L
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S477
N
V
D
Y
T
V
H
S
V
R
R
A
L
E
N
Rat
Rattus norvegicus
Q64560
1249
138274
S477
N
V
D
Y
T
V
H
S
V
R
R
A
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S582
G
I
D
Y
T
V
H
S
V
R
R
A
L
E
N
Chicken
Gallus gallus
XP_425591
1248
138209
S476
D
I
H
Y
T
V
H
S
V
R
R
A
L
E
N
Frog
Xenopus laevis
NP_001085380
1261
139671
S476
G
I
P
Y
T
V
N
S
V
R
R
A
L
E
N
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
S577
N
I
E
Y
S
P
Y
S
I
K
R
A
I
S
V
Honey Bee
Apis mellifera
XP_395521
1450
161968
S480
G
C
S
Y
S
P
Y
S
I
K
R
A
L
E
N
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
T527
N
L
K
W
T
P
Y
T
V
R
M
A
L
E
N
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
S477
G
I
A
Y
T
P
H
S
I
R
R
A
V
E
S
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
S506
G
I
P
V
S
P
Y
S
V
R
K
A
L
E
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
S586
G
I
P
V
S
P
Y
S
V
R
R
A
L
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
93.3
86.6
80
0
N.A.
40
46.6
53.3
60
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
93.3
86.6
0
N.A.
80
73.3
80
80
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
53.3
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
93
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
86
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
50
0
0
0
0
0
0
0
0
% H
% Ile:
0
65
0
0
0
0
0
0
22
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
15
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
79
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
43
0
0
0
0
0
8
0
0
0
0
0
0
0
79
% N
% Pro:
0
0
22
0
0
43
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
79
79
0
0
0
0
% R
% Ser:
0
0
8
0
29
0
0
86
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
65
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
15
0
15
0
50
0
0
72
0
0
0
8
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
72
0
0
36
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _